Cellular Repair
Restore, Don’t Replace
Polynucleotides
The Healers of the Skin
True skin restoration does not come from adding volume. It begins with repairing what has been weakened at a cellular level.
Polynucleotides are highly purified fragments of DNA that act as bio-stimulating messengers within the skin. Rather than filling lines or altering contours, they support tissue regeneration, improve hydration, and encourage the skin to repair itself from within. The result is not augmentation, but renewal.
This is regenerative medicine for the skin. Subtle, progressive, intelligent.
The Science of Regeneration
Polynucleotides work by stimulating fibroblast activity — the cells responsible for producing collagen and elastin. They also support microcirculation, enhance tissue repair, and improve skin elasticity over time.
Where traditional fillers add structure, polynucleotides improve the quality of the tissue itself. They calm inflammation, reduce oxidative stress, and strengthen the dermal matrix. Skin becomes healthier, more resilient, and more luminous — not stretched or volumised, but restored.
Regeneration is gradual. It unfolds over weeks, as your own biology responds.
Where Polynucleotides Excel
Polynucleotides are particularly suited to delicate or compromised skin — areas where refinement is needed without volume.
Applications include:
Under-eye rejuvenation – improving crepey texture, fine lines, and dark shadowing.
Neck and décolletage repair – restoring elasticity and softening etched lines.
Acne scarring support – enhancing dermal healing and improving skin quality.
Skin thinning and laxity – strengthening fragile tissue.
Overall skin vitality – enhancing glow, density, and resilience.
This is not about lifting or contouring. It is about rebuilding strength from within.
Treatment Experience
Polynucleotide treatments are typically delivered as a course of 2–3 sessions spaced several weeks apart. This allows time for biological response and collagen stimulation to develop progressively.
Anaesthesia: Topical numbing cream is used for comfort.
Downtime: Mild swelling or small injection marks may be visible for 24–48 hours.
Duration: Approximately 30 minutes depending on the treatment area.
Results: Improvements develop gradually over 4–8 weeks, with continued enhancement as collagen remodelling progresses.
A review appointment allows assessment of integration and long-term planning.
Who Is This Treatment For?
Polynucleotides are suited to individuals who prioritise skin quality over volume. Those who feel their skin appears thinner, tired, or less resilient, yet do not wish to alter facial structure, often find this treatment ideal.
It is particularly beneficial for patients seeking under-eye improvement without filler, or those wishing to support healing and regeneration after other procedures.
This is a treatment for those who value subtlety. For those who understand that true rejuvenation is biological, not cosmetic.
The Philosophy
Polynucleotides do not chase lines.
They restore integrity.
They do not inflate.
They regenerate.
The aim is not to look treated, but to look strengthened, skin that feels firmer, smoother, more alive.
Quiet improvement. Sustained vitality. Entirely your own.
FAQs
How Many Sessions Are Needed?
Most treatment plans involve two to three sessions spaced several weeks apart. This phased approach supports sustained regeneration and allows the skin to respond optimally. Maintenance may be recommended depending on individual skin quality and long-term goals.
How Long Do Results Last?
Longevity varies according to skin condition, age, lifestyle, and metabolic rate. Improvements in texture, elasticity, and resilience typically continue to develop over several months, with results often lasting 6–12 months before natural biological ageing progresses.
Are Polynucleotides the Same as Fillers?
No. Polynucleotides do not add volume or alter facial structure. They are regenerative treatments designed to improve skin quality at a cellular level. Where dermal fillers provide architectural support, polynucleotides enhance the integrity and vitality of the tissue itself.
Is This Treatment Suitable for the Under-Eye Area?
Yes. Polynucleotides are particularly well suited to the delicate under-eye region, where thin or crepey skin may not benefit from traditional fillers. By improving tissue strength and hydration, they refine texture without adding heaviness.
Is It Safe?
Polynucleotides are highly purified and biocompatible. As with any injectable treatment, suitability is determined through a full consultation and medical assessment. Mild swelling or bruising may occur, and rare complications are discussed transparently before treatment.
Who May Not Be Suitable?
This treatment may not be appropriate for those who are pregnant or breastfeeding, have active infection at the treatment site, or certain medical conditions affecting healing. A consultation ensures that treatment decisions are guided by safety and clinical judgement.
Can Polynucleotides Be Combined with Other Treatments?
Yes. Polynucleotides integrate well within a broader regenerative or aesthetic plan. They are often used alongside dermal fillers, neuromodulators, or energy-based treatments to enhance overall skin quality while structural refinements address contour and balance. Combination plans are approached thoughtfully and phased appropriately, allowing each treatment to integrate without overwhelming the tissue.
Will My Skin Look Different Immediately?
Polynucleotides are not designed to create dramatic, instant change. You may notice subtle hydration and mild plumping in the days following treatment, but the true improvement develops progressively. As collagen production increases and tissue strength improves, skin appears smoother, firmer, and more luminous, not altered, but restored.
Does the Treatment Change Facial Expression or Movement?
No. Polynucleotides do not affect muscle activity or alter expression. Their purpose is to improve the health and resilience of the skin itself. The face remains entirely natural in movement; the improvement lies in texture, elasticity, and vitality rather than structural modification.
How much does it cost?
Polynucleotide treatment is tailored to the individual, the area treated, the depth of regeneration required, and whether it forms part of a broader treatment plan all influence the overall investment. As a guide, treatment is typically priced per session, with many patients undertaking a short course for optimal results. During your consultation, a personalised plan will be discussed in detail, including transparent pricing and recommended session frequency. Generally prices start from £475 per session.
Polynucleotide treatments are gentle and biologically intelligent. They are typically delivered as a course of 2–3 sessions, spaced several weeks apart, allowing the skin time to respond and rebuild. Downtime is minimal. The improvement unfolds gradually, measured, progressive, natural.
This is not about forcing change. It is about supporting repair.